Fos ELISA Kit for Mouse(Mus musculus) | EIAab.comFos ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Fos(Gene name) > Mouse

Fos (Gene name),

Proto-oncogene c-Fos (Protein name ), FOS_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Fos;

Protein name:

Proto-oncogene c-Fos;

Alternative:

Cellular oncogene fos;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer; with JUN (By similarity). Interacts with MAFB. Component of the SMAD3/SMAD4/JUN/FOS complex required for syngernistic TGF-beta-mediated transcription at the AP1 promoter site. Interacts with SMAD3; the interaction is weak even on TGF-beta activation. Interacts with MAFB (By similarity). Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.

Function:

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling (By similarity). Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

380

Sequence:

50:

100:

150:

200:

250:

300:

350:

380:

FPSCAAAHRK | GSSSNEPSSD | SLSSPTLLAL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00170

KEGG:

mmu:14281

UniGene:

Mm.246513

SMR:

P01101

String:

P01101

Uniprot:

P01101

FOR

ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291h

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96T

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ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291m

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96T

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ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291b

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291r

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96T

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ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291p

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Proto-oncogene c-Fos

Cat.:

E1291c

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291c

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Packing:

96T

CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291r

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MSDS:

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Packing:

96T

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CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Proto-oncogene c-Fos

Cat.:

U1291h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse Proto-oncogene c-Fos

Cat.:

P1291Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Proto-oncogene c-Fos

Cat.:

P1291Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Proto-oncogene c-Fos

Cat.:

P1291Rb-r

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40ug/0.2ml

Monoclonal Antibody for Mouse Proto-oncogene c-Fos

Protein for Mouse Proto-oncogene c-Fos

Cat.:

R1291h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Mouse Proto-oncogene c-Fos

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini."
van Beveren C. , van Straaten F. , Curran T. , Mueller R. , Verma I.M.
Cell32:1241-1255(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene."
Meijlink F. , Curran T. , Miller A.D. , Verma I.M.
Proc. Natl. Acad. Sci. U.S.A.82:4987-4991(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary gland.
4.

"Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ."
Mittelstadt P.R. , Ashwell J.D.
J. Biol. Chem.276:29603-29610(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DSIPI
5.

"Molecular interpretation of ERK signal duration by immediate early gene products."
Murphy L.O. , Smith S. , Chen R.H. , Fingar D.C. , Blenis J.
Nat. Cell Biol.4:556-564(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-325; THR-331; SER-362 AND SER-374;FUNCTION;MUTAGENESIS OF THR-325; THR-331; PHE-343; TYR-345; SER-362 AND SER-374
6.

"Phosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced by platelet-derived growth factor."
Monje P. , Marinissen M.J. , Gutkind J.S.
Mol. Cell. Biol.23:7030-7043(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-232; THR-325; THR-331; SER-362 AND SER-374;FUNCTION;MUTAGENESIS OF THR-232; THR-325; THR-331 AND SER-374
7.

"Essential role of RSK2 in c-Fos-dependent osteosarcoma development."
David J.-P. , Mehic D. , Bakiri L. , Schilling A.F. , Mandic V. , Priemel M. , Idarraga M.H. , Reschke M.O. , Hoffmann O. , Amling M. , Wagner E.F.
J. Clin. Invest.115:664-672(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-362;FUNCTION
8.

"c-Fos activates and physically interacts with specific enzymes of the pathway of synthesis of polyphosphoinositides."
Alfonso Pecchio A.R. , Cardozo Gizzi A.M. , Renner M.L. , Molina-Calavita M. , Caputto B.L.
Mol. Biol. Cell22:4716-4725(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"The kinase c-Src and the phosphatase TC45 coordinately regulate c-Fos tyrosine phosphorylation and c-Fos phospholipid synthesis activation capacity."
Ferrero G.O. , Velazquez F.N. , Caputto B.L.
Oncogene31:3381-3391(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CDS1 AND PI4K2A;TYROSINE PHOSPHORYLATION BY SRC;MUTAGENESIS OF LYS-139; ARG-144 AND ARG-146

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